Search on: TRYPTOPHAN SYNTHETASE 
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Descriptor English:   Tryptophan Synthase 
Descriptor Spanish:   Triptófano Sintasa 
Descriptor Portuguese:   Triptofano Sintase 
Synonyms English:   Synthase, Tryptophan
Synthetase, Tryptophan
Tryptophan Synthetase  
Tree Number:   D08.811.520.241.300.850
D08.811.600.896
Definition English:   An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20. 
History Note English:   80; was TRYPTOPHAN SYNTHETASE 1972-79 (Prov 1972-73) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   14769 
Unique Identifier:   D014367 

Occurrence in VHL:
 

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